 Artist: Rock City Angels: mp3 download Genre(s): Metal Rock City Angels's discography:  Rock City Angels Year: 1986 Tracks: 11 The Rock City Angels got their start in the late '80s as a hair metal outfit. Performing their marque of high-energy voiceless rock during the high peak for the genre, the band managed to tone conclusion unrivaled album on Geffen before they were dropped during the alternative controversy explosion of 1992. They managed to reorganise and exploit on new material until, eventually, in 2000 they released their follow-up, an eponymic album on New Renaissance Records. |
Wednesday, 3 September 2008
Mp3 music: Rock City Angels
Friday, 15 August 2008
Stromedix Receives Orphan Drug Designation For STX-100 In Chronic Allograft Nephropathy
�Stromedix, Inc., a ergonomics company focused on innovational therapies for fibrosis and fibrotic organ failure, announced today that its pencil lead clinical prospect STX-100 has been granted orphan drug status by the US Food and Drug Administration ("FDA") for the treatment of chronic allograft renal disorder. Chronic allograft nephropathy (CAN), also known as chronic allograft dysfunction, is a fibrotic shape that is a leading cause of kidney graft failure. Approximately 20% of patients on the wait list for kidney transplantation in the United States are awaiting a retransplant of a failed transplant. There are no FDA-approved therapies for CAN.
STX-100 is a novel humanized monoclonal antibody licensed in 2007 from Biogen Idec. STX-100 targets integrin ?v?6 and exhibits significant anti-fibrotic activity in preclinical animal models of kidney, lung and liver disease. Stromedix initiated a Phase 1 clinical trial of STX-100 in early 2008.
Orphan do drugs status confers seven geezerhood of market exclusivity following FDA approval as well as certain tax advantages to companies that charter on the challenge of developing lifesaving drugs for small affected role populations.
"There is a clear medical need for therapies that prolong graft function in kidney transplant patients and that more than broadly stamp down fibrosis in other clinical settings," aforementioned Michael Gilman, Ph.D., CEO of Stromedix. "We have made rapid progress on STX-100 since obtaining the program from Biogen Idec last year. This activity by the FDA should facilitate the development of this dose for transplant patients."
About Stromedix
Stromedix, based in Cambridge, Massachusetts, is a biotechnology company focused on innovative therapies for fibrotic organ failure. Stromedix' investors include Atlas Venture, New Leaf Venture Partners, Frazier Healthcare Ventures, Bessemer Venture Partners and Red Abbey Venture Partners. Biogen Idec is besides a shareholder.
Stromedix
More information
STX-100 is a novel humanized monoclonal antibody licensed in 2007 from Biogen Idec. STX-100 targets integrin ?v?6 and exhibits significant anti-fibrotic activity in preclinical animal models of kidney, lung and liver disease. Stromedix initiated a Phase 1 clinical trial of STX-100 in early 2008.
Orphan do drugs status confers seven geezerhood of market exclusivity following FDA approval as well as certain tax advantages to companies that charter on the challenge of developing lifesaving drugs for small affected role populations.
"There is a clear medical need for therapies that prolong graft function in kidney transplant patients and that more than broadly stamp down fibrosis in other clinical settings," aforementioned Michael Gilman, Ph.D., CEO of Stromedix. "We have made rapid progress on STX-100 since obtaining the program from Biogen Idec last year. This activity by the FDA should facilitate the development of this dose for transplant patients."
About Stromedix
Stromedix, based in Cambridge, Massachusetts, is a biotechnology company focused on innovative therapies for fibrotic organ failure. Stromedix' investors include Atlas Venture, New Leaf Venture Partners, Frazier Healthcare Ventures, Bessemer Venture Partners and Red Abbey Venture Partners. Biogen Idec is besides a shareholder.
Stromedix
More information
Thursday, 7 August 2008
Kate Winslet - Luc Jacquet Making Fiction Gave Me Freedom
Making a fictional feature film allowed director Luc Jacquet to realise childhood dreams, he has explained.
The French documentary maker, whose star blush wine after the shock success of 2005 Oscar-winner March of the Penguins, was speaking beforehand of the release of his new film The Fox and the Child.
The Pathe
Friday, 27 June 2008
DJ Keyz and Lil Wayne
Artist: DJ Keyz and Lil Wayne
Genre(s):
Rap: Hip-Hop
Discography:
Collabo Edition 29
Year: 2006
Tracks: 21
Thursday, 19 June 2008
Indigo Girls line up fall tour plans
Indigo Girls [ tickets ]--currently rolling through the Western US as part of their latest tour--have added another run of shows to their calendar for the fall months.The duo of Amy Ray and Emily Saliers will concentrate on places east of the Mississippi River for the forthcoming outing, which kicks off Sept. 11 in Spartanburg, SC. The 17-city tour leg runs through early October.The Girls are currently gearing up for an appearance tomorrow night (6/18) in Tucson, AZ. The pair has 17 dates remaining on its current stretch, including a mid-June romp through the New England states; details are included below.Indigo Girls continue to support their 10th studio album, "Despite Our Differences," which surfaced in 2006 and peaked at No. 44 on The Billboard 200. The set--produced by Mitchell Froom (Paul McCartney, Sheryl Crow)--is the Indigo Girls' first album for Hollywood Records and features guest artists including Brandi Carlile and Pink. A couple of songs from the set are streaming at the performers' MySpace page. The Girls also have their own YouTube channel, where fans can check out all their latest videos.The Indigo Girls' next release will come in the form of a DVD--"Live at the Roxy"--which premiered in February on high-definition television channel HDNet and is scheduled to hit stores later this year.Ray's fourth solo album, "Didn't It Feel Kinder," drops July 22 with producer Greg Griffith (The Butchies, Le Tigre) behind the soundboard. "What ties the record together for me is this human yearning to be understood and the yearning to become empathetic with other people--how to love each other and be kind even when we're brutally angry," Ray said in a press release.
Saturday, 14 June 2008
LC's Time is Running Out
As the minutes ran down on Lauren Conrad's parking meter, TMZ's photog was faced with a tough choice: Spare a quarter and get on the "Hills" chick's good side or help fill the meter maid's quota.
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Sunday, 8 June 2008
Usher Wanted Lil Wayne And Beyonce's 'Love In This Club' Remix To Be 'Crazier Than The Original'
Usher has been making some boss moves for his latest LP, Here I Stand. Who else can commandeer appearances from both Jay-Z and Beyoncé, not to mention Will.I.Am, Young Jeezy and Lil "This is th-the remix baaaa-baaaay" Wayne?
"The remix to 'Love in This Club' features the Queen and ... one of the illest," Usher began to tell MTV Base of the version featuring Wayne and Beyoncé, whom he's dubbed the Queen of R&B.
Trumpeting Weezy F. Baby, he said, "Wayne, pound
for pound, is one of the illest in the game, and I wanted it to be something that would be a surprise, be a shock. Have shock value. That's what the remix is all about. 'Damn, did you hear the remix? It's crazier than the original. I like it more.' I just think it's great. Plies actually did a verse on it as well. He came with it. Everybody basically did their thing, and I am very happy that I was able to put that one in."
Although it's still unclear whether or not Ush will be dropping a video for his mega-reworking, he just let loose a video for another single, "Moving Mountains." The clip starts exactly where the video for the original "Love in This Club" ends, with Ush walking out of a steamy nightspot only to see everything around him — including the venue he just exited — in shambles. In "Moving Mountains," he has to climb to the highest peak to find his love.
Here I Stand comes out on Tuesday (May 27). The singer also confirmed to MTV Base what Polow Da Don told MTV News several weeks ago: that Polow was responsible for putting Young Jeezy on "Love in This Club," a move Usher obviously didn't mind.
"Jeezy is one of the greatest rappers of our generation," the singer noted.
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Monday, 2 June 2008
The Ting Tings' former label responds to 'cash in' claims
Switchflicker Records, the record company that released 1,000 vinyl copies of The Ting Tings' single, 'That's Not My Name'/ 'Great DJ' last year, have responded to claims by the band that they are now cashing in on the band's success.
The Ting Tings were critical on their blog about copies of their first release currently being sold at inflated prices - however, the label insisted they are doing nothing wrong as they own the stock and were selling selling remaining copies in line with the record's current value.
"Switchflicker Records supported The Ting Tings in the early stages of their career and released 1,000 copies of their debut single ('That's Not My Name'/'Great DJ') in June of last year," they explained in a statement. "Switchflicker has the invoice, order form and credit card receipt to prove that the label paid for these and not The Ting Tings. These seven-inch vinyl copies were sold at �2 each.
"Switchflicker is selling the remaining stock (which the label owns) at today�s market price. People have already sold unsigned copies for �50 on eBay)."
The label added that they were surprised the band had criticised them bearing in mind their financial status.
"The Ting Tings recently signed to Columbia Records for a reported �???," they said. "Switchflicker is, by contrast, a small independent label which has made no profit in respect of releasing the single, which brought the band to everyone's attention. Switchflicker wishes them well."
May 22, 2008 at Astoria, London -
May 23, 2008 at Leadmill, Sheffield -
May 24, 2008 at QMU, Glasgow -
More The Ting Tings tickets
The Ting Tings were critical on their blog about copies of their first release currently being sold at inflated prices - however, the label insisted they are doing nothing wrong as they own the stock and were selling selling remaining copies in line with the record's current value.
"Switchflicker Records supported The Ting Tings in the early stages of their career and released 1,000 copies of their debut single ('That's Not My Name'/'Great DJ') in June of last year," they explained in a statement. "Switchflicker has the invoice, order form and credit card receipt to prove that the label paid for these and not The Ting Tings. These seven-inch vinyl copies were sold at �2 each.
"Switchflicker is selling the remaining stock (which the label owns) at today�s market price. People have already sold unsigned copies for �50 on eBay)."
The label added that they were surprised the band had criticised them bearing in mind their financial status.
"The Ting Tings recently signed to Columbia Records for a reported �???," they said. "Switchflicker is, by contrast, a small independent label which has made no profit in respect of releasing the single, which brought the band to everyone's attention. Switchflicker wishes them well."
May 22, 2008 at Astoria, London -
May 23, 2008 at Leadmill, Sheffield -
May 24, 2008 at QMU, Glasgow -
More The Ting Tings tickets
Jon Blues Explosion Spencer
Artist: Jon Blues Explosion Spencer
Genre(s):
Rock
Indie
Discography:
Orange
Year: 2003
Tracks: 13
Extra Width and Mo Width
Year: 2003
Tracks: 22
Plastic Fang
Year: 2002
Tracks: 12
Live 16Oct2001@Vancouver
Year: 2001
Tracks: 16
Acme Plus
Year: 1999
Tracks: 20
Police won't question Olsen about Ledger
DUFFY
Rockferry (Mercury): A-
The Amy Winehouse comparisons are unavoidable: Duffy is another young, white chick from the UK whose music comes steeped in a retro ’60s vibe. But instead of sass and swagger, Duffy is all vulnerability, evoking memories of both Motown queen Mary Wells and English soul queen Dusty Springfield. The 23-year-old Welsh lass excels on a set of mostly broody ballads aided by hooky arrangements from the likes of Suede guitarist Bernard Butler; check out “Syrup & Honey,” a stripped-down nod to Otis Redding. The best example of the pop smarts of “Rockferry” is the sole up-tempo cut, the single “Mercy,” the track to download since you’ll want to hear it again as soon as it’s over.
The Amy Winehouse comparisons are unavoidable: Duffy is another young, white chick from the UK whose music comes steeped in a retro ’60s vibe. But instead of sass and swagger, Duffy is all vulnerability, evoking memories of both Motown queen Mary Wells and English soul queen Dusty Springfield. The 23-year-old Welsh lass excels on a set of mostly broody ballads aided by hooky arrangements from the likes of Suede guitarist Bernard Butler; check out “Syrup & Honey,” a stripped-down nod to Otis Redding. The best example of the pop smarts of “Rockferry” is the sole up-tempo cut, the single “Mercy,” the track to download since you’ll want to hear it again as soon as it’s over.
Jude Law’s son lands major film role
JUDE LAW’s young son RAFFERTY has landed his first major film role - starring alongside his father in sci-fi thriller REPOSSESSION MAMBO.
The 11-year-old will play a younger version of Law’s character in the movie, which is due for release next year (09).
Law’s ex-wife and Rafferty’s mother, Sadie Frost, is convinced the youngster is perfect for the role as he has inherited his dad’s good looks.
The 11-year-old will play a younger version of Law’s character in the movie, which is due for release next year (09).
Law’s ex-wife and Rafferty’s mother, Sadie Frost, is convinced the youngster is perfect for the role as he has inherited his dad’s good looks.
David MacKenzie joins 'Stain in the Snow'
Film an adaptation of Georges Simenon novel
CANNES -- Red-hot Scottish director David MacKenzie ("Hallam Foe") has boarded the psychological drama "Stain In the Snow," an adaptation of the 1948 novel by Georges Simenon, which Germany's Studio Hamburg International is producing.
Mackenzie will move to "Stain" after finishing his U.S. feature film debut, the sex comedy "Spread" starring Aston Kutcher and Anne Heche.
Studio Hamburg is currently developing the script together with Chorion, the UK-based executors of the Simenon estate. Shooting on the $11 million- $14 million pictures is planned for 2009 in Germany.
Studio Hamburg's Malte Grunert and Sytze van der Laan will produce with Chorion receiving an executive producer credit.
Set in an unnamed country obviously based on Nazi-occupied France, the novel is about a naive boy who descends into psychosis and depravity. It was previously adapted for the screen by Luis Saslavsky as "La Neige etait sale" (1952).
Simenon was one of the most prolific and acclaimed writers of the 20th century. His books have sold more than 600 million copies worldwide and dozens have been made into films. Simenon was president of the Cannes jury in 1960.
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Hall & Oates return to LA's Troubadour after 35 years
Hall & Oates returned to the Troubadour for two sold-out gigs this week -- their first shows at the legendary Los Angeles venue since the Philadelphia duo played their first shows in the city 35 years ago.
The band were in high spirits during their two-hour set Friday night (May 23), which saw them playing hits including 'Maneater', 'She's Gone' and 'Rich Girl' as well as Daryl Hall's solo material and some obscure numbers.
"We've never played this one outside Atlantic Records," Hall said before the band launched into 'Had I Known You Better Then', a melodic ballad on which John Oates sings lead vocals.
The duo drew a diverse crowd ranging from the senior set to 20-something indie kids, possibly due in part to younger bands including Death Cab For Cutie, Fall Out Boy and Flight Of The Conchords name-checking them as influences in recent months.
Hall & Oates were backed by a tight five-piece band featuring musicians such as Tom 'T-Bone' Wolk, with whom they've played for years.
The house lights were turned up throughout their entire set, giving the proceedings a homely, community vibe. "I see you all smiling, that's good," Hall said -- smiling himself throughout the entire night.
Adoring fans cheered and sang along to nearly every song, including a man who proudly displayed a license plate that read 'HNO4EVR'.
Hall & Oates returned to the stage for two encores, concluding the night with a rare performance of their massive 1981 hit 'Private Eyes'.
--By our Los Angeles staff.
Find out more about NME.
The band were in high spirits during their two-hour set Friday night (May 23), which saw them playing hits including 'Maneater', 'She's Gone' and 'Rich Girl' as well as Daryl Hall's solo material and some obscure numbers.
"We've never played this one outside Atlantic Records," Hall said before the band launched into 'Had I Known You Better Then', a melodic ballad on which John Oates sings lead vocals.
The duo drew a diverse crowd ranging from the senior set to 20-something indie kids, possibly due in part to younger bands including Death Cab For Cutie, Fall Out Boy and Flight Of The Conchords name-checking them as influences in recent months.
Hall & Oates were backed by a tight five-piece band featuring musicians such as Tom 'T-Bone' Wolk, with whom they've played for years.
The house lights were turned up throughout their entire set, giving the proceedings a homely, community vibe. "I see you all smiling, that's good," Hall said -- smiling himself throughout the entire night.
Adoring fans cheered and sang along to nearly every song, including a man who proudly displayed a license plate that read 'HNO4EVR'.
Hall & Oates returned to the stage for two encores, concluding the night with a rare performance of their massive 1981 hit 'Private Eyes'.
--By our Los Angeles staff.
Find out more about NME.
Harrison Ford, Cate Blanchett accused of being “capitalist puppets”
The Communist Party of St. Petersburg say the actors promote crude, anti-Soviet propaganda in their new film, Indiana Jones and the Kingdom of the Crystal Skull; and have urged Russia’s movie-going public to boycott the film and told Ford, 65, not to visit the country.
Crystal Skull, directed by Steven Spielberg, is the fourth movie in the lucrative movie franchise that began in 1981. It’s set in the Cold War in 1957 and pits Indiana Jones against a sinister KGB agent, played by Blanchett, who leads a ruthless team of Soviet spies in the hunt for a skull endowed with mystical powers.
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